Wearable Biomarkers Assess Associations With Anxiety

A systematic review and meta-analysis by UK researchers (final search Sep 21, 2025) examined associations between wrist-worn wearable digital biomarkers and anxiety in adults, synthesizing 44 studies from 42 articles (sample sizes 17–170,320). Meta-analyses found no associations for four sleep metrics, while lower physical activity and higher heart rate correlated with greater anxiety; machine-learning models showed variable performance and improved when combined with other data sources.
Key Points
- 1Meta-analysis finds no association between four wearable sleep metrics and anxiety (44 studies).
- 2Lower physical activity and elevated heart rate correlate with greater anxiety symptoms, indicating physiological links.
- 3Integrate wearable data with self-report and clinical information to improve screening and predictive performance.
Scoring Rationale
Peer-reviewed systematic review with 44 studies supports moderate evidence; heterogeneous methods and small samples limit definitive conclusions.
Sources
Public references used for this report.
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