Machine Learning Identifies NPAR Prognostic Value

Researchers at The First Affiliated Hospital of Zhengzhou University retrospectively analyzed 160 adult-type diffuse glioma patients (June 2019–September 2021) and used LASSO, XGBoost, and random forest to build prognostic models. They found preoperative neutrophil percentage–to–albumin ratio (NPAR), platelet-to-mean platelet volume ratio, and age predicted overall and progression-free survival, with C-indexes of 0.731 (training) and 0.763 (validation).
Scoring Rationale
Moderate novelty and practical model development, limited by single-center retrospective cohort and need for external validation.
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