Machine Learning Detects Left Ventricular Hypertrophy

A systematic review and meta-analysis registered CRD42024617183 pooled 25 studies through November 12, 2025 that evaluated machine learning models for detecting left ventricular hypertrophy (LVH). Pooled results: ECG-based models sensitivity 0.76 (95% CI 0.66–0.84) and specificity 0.84 (95% CI 0.78–0.89); clinical-feature models sensitivity 0.78 and specificity 0.71; echocardiography-based models sensitivity 0.71–0.94 and specificity 0.67–0.96, though extreme heterogeneity limits confidence and necessitates further imaging-focused research.