Models Predict Frailty in Older Adults With Diabetes

A systematic review and meta-analysis published in J Med Internet Res (2026) evaluated models predicting physical and cognitive frailty in older adults with diabetes, searching six databases through December 2025 and including 24 studies (32 diagnostic models). Pooled discrimination was strong (AUC 0.851, 95% CI 0.820–0.882), logistic regression outperformed machine learning, but all studies had high risk of bias, limiting clinical utility.
Scoring Rationale
Solid systematic synthesis with pooled metrics; constrained by high risk of bias and limited external validation.
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