Exercise Rejuvenates Middle-Aged Brains Seven Months
Researchers from the University of Pittsburgh and AdventHealth Research Institute report in the Journal of Sport and Health Science that 130 adults aged 26–58 who completed 150 minutes of aerobic exercise weekly for 12 months showed MRI-derived brain-age measures about seven months younger. The randomized trial found this structural change despite no clear explanatory effects from fitness, blood pressure, body composition, or measured brain proteins, leaving mechanisms unknown.
Scoring Rationale
Strong randomized trial evidence and actionable exercise guidance, but mechanisms remain unexplained and sample size moderate.
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