Researchminicircle dnasmar motifbiomarkersliquid biopsy

Dual-Biomarkers Enable Sensitive Blood and Urine Detection

pubmed.ncbi.nlm.nih.gov

|February 24, 2026

3.8

Relevance Score

Dual-Biomarkers Enable Sensitive Blood and Urine Detection

A study presents tumor-activatable minicircles that encode dual biomarkers and incorporate scaffold/matrix attachment region motifs, designed to provide sensitive and sustained cancer detection through blood and urine-based assays. The report emphasizes blood- and urine-based cancer diagnostics using these minicircles.

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Moderate novelty and translational promise, but RSS-only source and limited methodological details reduce confidence and impact.

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Dual-biomarkers encoding tumor-activatable minicircles with scaffold/matrix attachment region motif for sensitive and sustained blood and urine-based cancer detection
pubmed.ncbi.nlm.nih.gov
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