Crinetics Gains Analyst Upgrades, Strong Trial Results

Crinetics Pharmaceuticals on Jan. 12 received a Buy upgrade from Goldman Sachs (Richard Law) with a $67 target after trial results showed a 67% reduction in A4 in Cohort 4 and sustained androgen reductions in seven of eight participants despite glucocorticoid dose cuts. Citizens slightly lowered its $105 target while keeping Outperform; analysts cited Palsonify’s positive early experience and preliminary Q4 net product revenue above $5 million.
Scoring Rationale
Moderate investor and clinical relevance from replicated trial data, offset by niche scope and promotional, non-peer-reviewed reporting.
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