SeekRBP Improves RBP Identification For Phages

Researchers present SeekRBP, a sequence–structure framework submitted to arXiv on 5 March 2026 that detects receptor-binding proteins (RBPs) using a multi-armed bandit negative-sampling strategy and multimodal protein language plus structural embeddings. Benchmarks show SeekRBP outperforms static sampling approaches, and a Vibrio phage case study demonstrates improved host prediction, suggesting utility for large-scale annotation and synthetic biology applications.
Scoring Rationale
Strong methodological innovation and practical gains drive score, limited by preprint status and constrained evaluation scope.
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