FKSUDDAPre Predicts Drug–Disease Associations With High Accuracy
Zuo et al. publish FKSUDDAPre on February 5, 2026, a framework that predicts drug–disease associations using Mol2vec and K-BERT for drugs and MeSH with DeepWalk for diseases. The system uses AMDKSU resampling, F-test feature selection, and an XGBoost/Decision Tree/Random Forest/HyperFast ensemble, achieves average AUC 0.9725 (≈3.88% improvement), and validates many top candidates for Alzheimer’s and Parkinson’s disease.
Scoring Rationale
Peer-reviewed validation, strong performance, and usable code increase score; novelty is moderate compared to existing DDA methods.
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Sources
- Read OriginalFKSUDDAPre: A drug–disease association prediction framework based on F-TEST feature selection and AMDKSU resampling with interpretability analysisjournals.plos.org
