Fiber Deficiency Impairs Amygdala-Based Memory in Aging Brains
Ohio State University researchers published a study in Brain, Behavior, and Immunity finding that three days of refined, fiber-poor diets impaired amygdala-dependent emotional memory in aged rats. The diets rapidly reduced gut-derived butyrate, increased neuroinflammation, and caused microglial mitochondrial dysfunction. The findings imply low dietary fiber could weaken older adults' ability to learn from risky experiences, increasing exploitation vulnerability.
Scoring Rationale
Peer-reviewed animal study reveals rapid diet–gut–brain mechanism, but findings remain limited by preclinical evidence for direct human translation.
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