FFRangio Software Matches Wire-Based Coronary Outcomes

A large international randomized trial presented at ACC.26 and published in the New England Journal of Medicine found that FFRangio, an AI-driven image-based software, produced similar one-year outcomes to invasive wire-based fractional flow reserve in 1,930 patients (6.9% vs 7.1% primary events). FFRangio was faster to perform and avoided additional catheters or hyperemic drugs, potentially increasing physiologic testing adoption pending cost analyses.