Deep Learning Detects Osteoporosis From Medical Imaging

Researchers from Guangzhou University of Traditional Chinese Medicine conducted a systematic review and meta-analysis, searching PubMed, Embase, Cochrane, and Web of Science through May 16, 2024. They included 60 studies totaling 66,195 participants and found high pooled sensitivity and specificity for x-ray and CT–based deep learning models (x-ray appendicular SEN 0.97 SPC 0.90; CT lumbar SEN 0.91 SPC 0.92), but identified few MRI studies and limited external validation.
Scoring Rationale
Comprehensive synthesis and robust pooled metrics, offset by limited MRI evidence and inadequate external validation across studies.
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